Risk, genotype, and cardiovascular disease.
نویسنده
چکیده
T he sense of loss one experiences after missing a diagnosis, or underestimating the risk, of a life-threatening disorder is difficult to forget. This is particularly true if the disorder affects a young, otherwise healthy individual. Presymptomatic diagnosis of most cardiovascular disease is challenging, even in disorders that are clearly inherited, and risk assessment is frequently inadequate. The possibility of predicting risk of morbidity and mortality from cardiovascular disease at, or even before, birth would be a fantastic addition to our clinical capability. In a series of recent articles, one of which is published in this issue of Circulation,' investigators have begun to address the need for improved risk assessment in a specific inherited cardiovascular disease, familial hypertrophic cardiomyopathy, through identification of disease-associated genetic mutations.
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عنوان ژورنال:
- Circulation
دوره 86 2 شماره
صفحات -
تاریخ انتشار 1992